【藥品名稱】
通用名稱：鹽酸多巴胺注射液
英文名稱：Dopamine Hydrochloride Injection
漢語拼音：Yansuan Duoba′an Zhusheye
【成份】
鹽(yan)(yan)酸多巴(ba)胺。其化學(xue)名稱為：4-(2-氨基乙基)-1，2-苯二酚鹽(yan)(yan)酸鹽(yan)(yan)。分(fen)子(zi)式(shi)：C8H11NO2?HCl分(fen)子(zi)量：189.64
【性狀】
本品為無色的澄(cheng)明液體。
【適應癥】
適用(yong)(yong)于(yu)心肌梗死、創傷、內毒素敗血(xue)(xue)癥、心臟手術、腎功能(neng)衰(shuai)竭、充血(xue)(xue)性心力衰(shuai)竭等(deng)引起的休克(ke)綜合征；補充血(xue)(xue)容量(liang)后休克(ke)仍(reng)不能(neng)糾正者(zhe)，尤(you)其(qi)有少尿及(ji)周(zhou)圍血(xue)(xue)管阻力正常或較低的休克(ke)。由于(yu)本品可增加心排血(xue)(xue)量(liang)，也用(yong)(yong)于(yu)洋(yang)地黃和利尿劑無效(xiao)的心功能(neng)不全
【用法用量】
成人常用量靜脈注射，開始時每分鐘按體重1-5μg/kg，10分鐘內以每分鐘1-4μg/kg速度遞增，以達到最大療效。慢性頑固性心力衰竭，靜滴開始時，每分鐘按體重0.5-2μg/kg逐漸遞增。多數病人按1-3（μg/kg）/分鐘給予即可生效。閉塞性血管病變患者，靜滴開始時按1（μg/kg）/分鐘，逐增至5（μg/kg）/分鐘，直到20(μg/kg)/分鐘，以達到最滿意效應。如危重病例，先按5(μg/kg)/分鐘滴注，然后以5-10(μg/kg)/分鐘遞增至20-50(μg/kg)/分鐘，以達到滿意效應。或本品20mg加入5%葡萄糖注射液200-300ml中靜滴，開始時按75-100μg/分鐘滴入，以后根據血壓情況，可加快速度和加大濃度，但最大劑量不超過每分鐘500μg。
【不良反應】
常見的有胸(xiong)痛、呼吸困難、心悸、心律(lv)失常(尤其用(yong)大劑量(liang)(liang))、全身軟(ruan)弱(ruo)無(wu)力感；心跳緩(huan)慢、頭痛、惡心嘔吐(tu)者少見。長期應用(yong)大劑量(liang)(liang)或(huo)小劑量(liang)(liang)用(yong)于(yu)外(wai)(wai)周血(xue)(xue)(xue)管病(bing)患者，出(chu)現的反應有手足疼痛或(huo)手足發涼；外(wai)(wai)周血(xue)(xue)(xue)管長時(shi)期收縮，可(ke)能(neng)導致局部(bu)壞死或(huo)壞疽；過量(liang)(liang)時(shi)可(ke)出(chu)現血(xue)(xue)(xue)壓升高，此時(shi)應停藥，必要時(shi)給予(yu)α受(shou)體阻滯劑。
【禁忌】
對本品(pin)任何成分過敏(min)者(zhe)禁用(yong)。
【注意事項】
(1)交(jiao)叉過敏(min)(min)反應(ying)：對(dui)(dui)其他(ta)擬交(jiao)感胺(an)(an)類藥(yao)(yao)高(gao)(gao)度(du)敏(min)(min)感的(de)(de)病(bing)人(ren)(ren)，可(ke)能對(dui)(dui)本(ben)品(pin)(pin)(pin)也(ye)異常敏(min)(min)感。 (2)對(dui)(dui)人(ren)(ren)體(ti)研究(jiu)尚不(bu)(bu)充分(fen)，動物實驗未(wei)(wei)見有(you)致畸。給(gei)妊娠鼠(shu)有(you)導(dao)致新生(sheng)仔鼠(shu)存活率降(jiang)低(di)(di)，而且存活者(zhe)潛在(zai)形成(cheng)白內障的(de)(de)報(bao)道(dao)。孕婦應(ying)用(yong)(yong)(yong)(yong)(yong)時(shi)必(bi)須(xu)權衡(heng)利弊。 (3)本(ben)品(pin)(pin)(pin)是(shi)否(fou)排(pai)入乳汁未(wei)(wei)定(ding)，但在(zai)乳母應(ying)用(yong)(yong)(yong)(yong)(yong)未(wei)(wei)發現(xian)問題(ti)。 (4)本(ben)品(pin)(pin)(pin)在(zai)小兒應(ying)用(yong)(yong)(yong)(yong)(yong)未(wei)(wei)有(you)充分(fen)研究(jiu)。 (5)本(ben)品(pin)(pin)(pin)在(zai)老(lao)年人(ren)(ren)應(ying)用(yong)(yong)(yong)(yong)(yong)未(wei)(wei)有(you)充分(fen)研究(jiu)，但未(wei)(wei)見報(bao)告發生(sheng)問題(ti)。 (6)下列情(qing)況應(ying)慎(shen)用(yong)(yong)(yong)(yong)(yong)： ①嗜鉻細(xi)胞瘤(liu)患者(zhe)不(bu)(bu)宜使(shi)用(yong)(yong)(yong)(yong)(yong)； ②閉塞性(xing)(xing)(xing)(xing)(xing)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)(guan)病(bing)(或(huo)有(you)既(ji)往史者(zhe))，包括動脈(mo)栓(shuan)塞、動脈(mo)粥(zhou)樣硬化、血(xue)(xue)(xue)(xue)(xue)(xue)(xue)栓(shuan)閉塞性(xing)(xing)(xing)(xing)(xing)脈(mo)管(guan)(guan)炎(yan)、凍傷(如凍瘡)、糖(tang)尿病(bing)性(xing)(xing)(xing)(xing)(xing)動脈(mo)內膜炎(yan)、雷諾氏病(bing)等(deng)慎(shen)用(yong)(yong)(yong)(yong)(yong)； ③對(dui)(dui)肢端循(xun)環不(bu)(bu)良的(de)(de)病(bing)人(ren)(ren)，須(xu)嚴(yan)密監測，注(zhu)(zhu)意壞死(si)及(ji)壞疽的(de)(de)可(ke)能性(xing)(xing)(xing)(xing)(xing)； ④頻(pin)繁的(de)(de)室(shi)性(xing)(xing)(xing)(xing)(xing)心(xin)(xin)律失(shi)常時(shi)應(ying)用(yong)(yong)(yong)(yong)(yong)本(ben)品(pin)(pin)(pin)也(ye)須(xu)謹(jin)慎(shen)。 (7)在(zai)滴(di)(di)注(zhu)(zhu)本(ben)品(pin)(pin)(pin)時(shi)須(xu)進行血(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)(ya)(ya)、心(xin)(xin)排(pai)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)量(liang)(liang)(liang)(liang)、心(xin)(xin)電圖及(ji)尿量(liang)(liang)(liang)(liang)的(de)(de)監測。 (8)給(gei)藥(yao)(yao)說明 ①應(ying)用(yong)(yong)(yong)(yong)(yong)多(duo)巴(ba)(ba)胺(an)(an)治療前必(bi)須(xu)先糾(jiu)正(zheng)低(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)容(rong)量(liang)(liang)(liang)(liang)。 ②在(zai)滴(di)(di)注(zhu)(zhu)前必(bi)須(xu)稀(xi)釋，稀(xi)釋液(ye)的(de)(de)濃度(du)取決(jue)于(yu)(yu)劑(ji)量(liang)(liang)(liang)(liang)及(ji)個體(ti)需(xu)要的(de)(de)液(ye)量(liang)(liang)(liang)(liang)，若(ruo)不(bu)(bu)需(xu)要擴容(rong)，可(ke)用(yong)(yong)(yong)(yong)(yong)0.8mg/ml溶(rong)液(ye)，如有(you)液(ye)體(ti)潴留，可(ke)用(yong)(yong)(yong)(yong)(yong)1.6-3.2mg/ml溶(rong)液(ye)。中、小劑(ji)量(liang)(liang)(liang)(liang)對(dui)(dui)周(zhou)圍血(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)(guan)阻力無作用(yong)(yong)(yong)(yong)(yong)，用(yong)(yong)(yong)(yong)(yong)于(yu)(yu)處理低(di)(di)心(xin)(xin)排(pai)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)量(liang)(liang)(liang)(liang)引起(qi)(qi)的(de)(de)低(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)(ya)(ya)；較大劑(ji)量(liang)(liang)(liang)(liang)則用(yong)(yong)(yong)(yong)(yong)于(yu)(yu)提高(gao)(gao)周(zhou)圍血(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)(guan)阻力以(yi)糾(jiu)正(zheng)低(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)(ya)(ya)。 ③選用(yong)(yong)(yong)(yong)(yong)粗大的(de)(de)靜脈(mo)作靜注(zhu)(zhu)或(huo)靜滴(di)(di)，以(yi)防藥(yao)(yao)液(ye)外溢，及(ji)產(chan)生(sheng)組織(zhi)壞死(si)；如確已發生(sheng)液(ye)體(ti)外溢，可(ke)用(yong)(yong)(yong)(yong)(yong)5-10mg酚妥(tuo)拉明稀(xi)釋溶(rong)液(ye)在(zai)注(zhu)(zhu)射部(bu)位作浸(jin)潤(run)。 ④靜滴(di)(di)時(shi)應(ying)控制每(mei)分(fen)鐘(zhong)滴(di)(di)速(su)，滴(di)(di)注(zhu)(zhu)的(de)(de)速(su)度(du)和時(shi)間需(xu)根(gen)據(ju)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)(ya)(ya)、心(xin)(xin)率、尿量(liang)(liang)(liang)(liang)、外周(zhou)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)(guan)灌流(liu)情(qing)況、異位搏動出(chu)現(xian)與否(fou)等(deng)而定(ding)，可(ke)能時(shi)應(ying)做心(xin)(xin)排(pai)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)量(liang)(liang)(liang)(liang)測定(ding)。 ⑤休克糾(jiu)正(zheng)時(shi)即減(jian)慢(man)滴(di)(di)速(su)。 ⑥遇有(you)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)(guan)過度(du)收(shou)縮(suo)引起(qi)(qi)舒張壓(ya)(ya)(ya)(ya)不(bu)(bu)成(cheng)比例升高(gao)(gao)和脈(mo)壓(ya)(ya)(ya)(ya)減(jian)小、尿量(liang)(liang)(liang)(liang)減(jian)少、心(xin)(xin)率增快或(huo)出(chu)現(xian)心(xin)(xin)律失(shi)常，滴(di)(di)速(su)必(bi)須(xu)減(jian)慢(man)或(huo)暫停(ting)滴(di)(di)注(zhu)(zhu)。 ⑦如在(zai)滴(di)(di)注(zhu)(zhu)多(duo)巴(ba)(ba)胺(an)(an)時(shi)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)(ya)(ya)繼續下降(jiang)或(huo)經調整劑(ji)量(liang)(liang)(liang)(liang)仍持(chi)續低(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)(ya)(ya)，應(ying)停(ting)用(yong)(yong)(yong)(yong)(yong)多(duo)巴(ba)(ba)胺(an)(an)，改用(yong)(yong)(yong)(yong)(yong)更強(qiang)的(de)(de)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)管(guan)(guan)收(shou)縮(suo)藥(yao)(yao)。 ⑧突然(ran)停(ting)藥(yao)(yao)可(ke)產(chan)生(sheng)嚴(yan)重(zhong)低(di)(di)血(xue)(xue)(xue)(xue)(xue)(xue)(xue)壓(ya)(ya)(ya)(ya)，故停(ting)用(yong)(yong)(yong)(yong)(yong)時(shi)應(ying)逐(zhu)漸遞減(jian)。
【特殊人群用藥】
兒童注意事項：
未進行該項實驗且無可靠參考文獻。
妊娠與哺乳期注意事項：
未進行該項實驗且無可靠參考文獻。
【藥物相互作用】
(1)與(yu)(yu)硝普(pu)鈉、異丙腎(shen)上腺(xian)素、多(duo)(duo)(duo)巴(ba)(ba)(ba)酚丁(ding)胺合(he)用(yong)(yong)(yong)(yong)(yong)(yong)，注意心(xin)(xin)(xin)(xin)(xin)(xin)排血(xue)量的(de)改變，比單(dan)用(yong)(yong)(yong)(yong)(yong)(yong)本(ben)品(pin)時反(fan)應(ying)(ying)不(bu)同(tong)(tong)。 (2)大劑量多(duo)(duo)(duo)巴(ba)(ba)(ba)胺與(yu)(yu)α受體(ti)阻滯(zhi)劑如(ru)酚芐(xia)明、酚妥(tuo)拉明、妥(tuo)拉唑林(Tolazoline)等同(tong)(tong)用(yong)(yong)(yong)(yong)(yong)(yong)，后者的(de)擴血(xue)管(guan)(guan)(guan)效(xiao)(xiao)應(ying)(ying)可(ke)(ke)被(bei)本(ben)品(pin)的(de)外(wai)周(zhou)血(xue)管(guan)(guan)(guan)的(de)收縮(suo)作(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)拮抗(kang)。 (3)與(yu)(yu)全麻(ma)藥(yao)(尤其是環丙烷或鹵代(dai)碳(tan)氫化合(he)物)合(he)用(yong)(yong)(yong)(yong)(yong)(yong)由(you)于(yu)(yu)(yu)后者可(ke)(ke)使(shi)(shi)心(xin)(xin)(xin)(xin)(xin)(xin)肌對多(duo)(duo)(duo)巴(ba)(ba)(ba)胺異常(chang)(chang)(chang)敏感，引起(qi)室(shi)性(xing)心(xin)(xin)(xin)(xin)(xin)(xin)律(lv)(lv)失(shi)常(chang)(chang)(chang)。 (4)與(yu)(yu)β受體(ti)阻滯(zhi)劑同(tong)(tong)用(yong)(yong)(yong)(yong)(yong)(yong)，可(ke)(ke)拮抗(kang)多(duo)(duo)(duo)巴(ba)(ba)(ba)胺對心(xin)(xin)(xin)(xin)(xin)(xin)臟的(de)β1受體(ti)作(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)。 (5)與(yu)(yu)硝酸(suan)酯(zhi)類同(tong)(tong)用(yong)(yong)(yong)(yong)(yong)(yong)，可(ke)(ke)減(jian)弱硝酸(suan)酯(zhi)的(de)抗(kang)心(xin)(xin)(xin)(xin)(xin)(xin)絞痛及(ji)多(duo)(duo)(duo)巴(ba)(ba)(ba)胺的(de)升壓效(xiao)(xiao)應(ying)(ying)。 (6)與(yu)(yu)利尿藥(yao)同(tong)(tong)用(yong)(yong)(yong)(yong)(yong)(yong)，一方(fang)面由(you)于(yu)(yu)(yu)本(ben)品(pin)作(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)于(yu)(yu)(yu)多(duo)(duo)(duo)巴(ba)(ba)(ba)胺受體(ti)擴張(zhang)腎(shen)血(xue)管(guan)(guan)(guan)，使(shi)(shi)腎(shen)血(xue)流(liu)量增(zeng)加(jia)，可(ke)(ke)增(zeng)加(jia)利尿作(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)；另一方(fang)面本(ben)品(pin)自身還有直接的(de)利尿作(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)。 (7)與(yu)(yu)胍乙啶(ding)同(tong)(tong)用(yong)(yong)(yong)(yong)(yong)(yong)時，可(ke)(ke)加(jia)強(qiang)多(duo)(duo)(duo)巴(ba)(ba)(ba)胺的(de)加(jia)壓效(xiao)(xiao)應(ying)(ying)，使(shi)(shi)胍乙啶(ding)的(de)降壓作(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)減(jian)弱，導致高(gao)血(xue)壓及(ji)心(xin)(xin)(xin)(xin)(xin)(xin)律(lv)(lv)失(shi)常(chang)(chang)(chang)。 (8)與(yu)(yu)三環類抗(kang)抑郁(yu)藥(yao)同(tong)(tong)時應(ying)(ying)用(yong)(yong)(yong)(yong)(yong)(yong)，可(ke)(ke)能(neng)增(zeng)加(jia)多(duo)(duo)(duo)巴(ba)(ba)(ba)胺的(de)心(xin)(xin)(xin)(xin)(xin)(xin)血(xue)管(guan)(guan)(guan)作(zuo)用(yong)(yong)(yong)(yong)(yong)(yong)，引起(qi)心(xin)(xin)(xin)(xin)(xin)(xin)律(lv)(lv)失(shi)常(chang)(chang)(chang)、心(xin)(xin)(xin)(xin)(xin)(xin)動過(guo)速、高(gao)血(xue)壓。 (9)與(yu)(yu)單(dan)胺氧(yang)化酶抑制劑同(tong)(tong)用(yong)(yong)(yong)(yong)(yong)(yong)，可(ke)(ke)延長(chang)及(ji)加(jia)強(qiang)多(duo)(duo)(duo)巴(ba)(ba)(ba)胺的(de)效(xiao)(xiao)應(ying)(ying)；已知本(ben)品(pin)是通過(guo)單(dan)胺氧(yang)化酶代(dai)謝，在(zai)給多(duo)(duo)(duo)巴(ba)(ba)(ba)胺前2-3周(zhou)曾接受單(dan)胺氧(yang)化酶抑制劑的(de)病人，初量至(zhi)少減(jian)到常(chang)(chang)(chang)用(yong)(yong)(yong)(yong)(yong)(yong)劑量的(de)1/10。 (10)與(yu)(yu)苯(ben)妥(tuo)英鈉同(tong)(tong)時靜(jing)注可(ke)(ke)產(chan)生低血(xue)壓與(yu)(yu)心(xin)(xin)(xin)(xin)(xin)(xin)動過(guo)緩。在(zai)用(yong)(yong)(yong)(yong)(yong)(yong)多(duo)(duo)(duo)巴(ba)(ba)(ba)胺時，如(ru)必(bi)須(xu)用(yong)(yong)(yong)(yong)(yong)(yong)苯(ben)妥(tuo)英納抗(kang)驚(jing)厥治療時，則須(xu)考(kao)慮兩(liang)藥(yao)交替使(shi)(shi)用(yong)(yong)(yong)(yong)(yong)(yong)。
【藥理作用】
激動(dong)(dong)(dong)交感(gan)神經系統(tong)腎(shen)(shen)(shen)上(shang)腺素(su)受(shou)體(ti)和(he)位(wei)于(yu)腎(shen)(shen)(shen)、腸系膜、冠狀動(dong)(dong)(dong)脈(mo)、腦動(dong)(dong)(dong)脈(mo)的(de)(de)多(duo)巴胺(an)受(shou)體(ti)其效應(ying)為(wei)劑量(liang)(liang)(liang)(liang)(liang)(liang)依賴性(xing)。 (1)小劑量(liang)(liang)(liang)(liang)(liang)(liang)時(每(mei)分(fen)鐘(zhong)按(an)體(ti)重(zhong)(zhong)0.5-2μg/kg)，主要作(zuo)用(yong)于(yu)多(duo)巴胺(an)受(shou)體(ti)，使(shi)(shi)腎(shen)(shen)(shen)及腸系膜血(xue)(xue)(xue)管(guan)擴(kuo)張，腎(shen)(shen)(shen)血(xue)(xue)(xue)流量(liang)(liang)(liang)(liang)(liang)(liang)及腎(shen)(shen)(shen)小球濾過率增(zeng)加(jia)，尿量(liang)(liang)(liang)(liang)(liang)(liang)及鈉排泄量(liang)(liang)(liang)(liang)(liang)(liang)增(zeng)加(jia)； (2)小到中等劑量(liang)(liang)(liang)(liang)(liang)(liang)(每(mei)分(fen)鐘(zhong)按(an)體(ti)重(zhong)(zhong)2-10μg/kg)，能(neng)直接激動(dong)(dong)(dong)β1受(shou)體(ti)及間接促使(shi)(shi)去甲腎(shen)(shen)(shen)上(shang)腺素(su)自儲藏部(bu)位(wei)釋(shi)放，對(dui)心(xin)(xin)(xin)肌產生正(zheng)性(xing)應(ying)力(li)(li)作(zuo)用(yong)，使(shi)(shi)心(xin)(xin)(xin)肌收(shou)(shou)縮(suo)力(li)(li)及心(xin)(xin)(xin)搏量(liang)(liang)(liang)(liang)(liang)(liang)增(zeng)加(jia)，最(zui)終使(shi)(shi)心(xin)(xin)(xin)排血(xue)(xue)(xue)量(liang)(liang)(liang)(liang)(liang)(liang)增(zeng)加(jia)、收(shou)(shou)縮(suo)壓(ya)(ya)(ya)升高、脈(mo)壓(ya)(ya)(ya)可能(neng)增(zeng)大(da)，舒張壓(ya)(ya)(ya)無變(bian)(bian)化或有輕度升高，外周(zhou)總阻力(li)(li)常無改(gai)變(bian)(bian)，冠脈(mo)血(xue)(xue)(xue)流及耗(hao)氧改(gai)善； (3)大(da)劑量(liang)(liang)(liang)(liang)(liang)(liang)時(每(mei)分(fen)鐘(zhong)按(an)體(ti)重(zhong)(zhong)大(da)于(yu)10μg/kg)，激動(dong)(dong)(dong)α受(shou)體(ti)，導致(zhi)(zhi)(zhi)周(zhou)圍血(xue)(xue)(xue)管(guan)阻力(li)(li)增(zeng)加(jia)，腎(shen)(shen)(shen)血(xue)(xue)(xue)管(guan)收(shou)(shou)縮(suo)，腎(shen)(shen)(shen)血(xue)(xue)(xue)流量(liang)(liang)(liang)(liang)(liang)(liang)及尿量(liang)(liang)(liang)(liang)(liang)(liang)反而減(jian)(jian)少(shao)。由于(yu)心(xin)(xin)(xin)排血(xue)(xue)(xue)量(liang)(liang)(liang)(liang)(liang)(liang)及周(zhou)圍血(xue)(xue)(xue)管(guan)阻力(li)(li)增(zeng)加(jia)，致(zhi)(zhi)(zhi)使(shi)(shi)收(shou)(shou)縮(suo)壓(ya)(ya)(ya)及舒張壓(ya)(ya)(ya)均增(zeng)高。 ①對(dui)心(xin)(xin)(xin)臟β1受(shou)體(ti)激動(dong)(dong)(dong)，增(zeng)加(jia)心(xin)(xin)(xin)肌收(shou)(shou)縮(suo)力(li)(li)作(zuo)用(yong)強的(de)(de)多(duo)； ②由于(yu)增(zeng)加(jia)腎(shen)(shen)(shen)和(he)腸系膜的(de)(de)血(xue)(xue)(xue)流量(liang)(liang)(liang)(liang)(liang)(liang)，可防止由這些器官(guan)缺(que)血(xue)(xue)(xue)所(suo)致(zhi)(zhi)(zhi)的(de)(de)休(xiu)克惡性(xing)發展。在(zai)相(xiang)同的(de)(de)增(zeng)加(jia)心(xin)(xin)(xin)肌收(shou)(shou)縮(suo)力(li)(li)情況下，致(zhi)(zhi)(zhi)心(xin)(xin)(xin)律失常和(he)增(zeng)加(jia)心(xin)(xin)(xin)肌耗(hao)氧的(de)(de)作(zuo)用(yong)較弱。總之，多(duo)巴胺(an)對(dui)于(yu)伴有心(xin)(xin)(xin)肌收(shou)(shou)縮(suo)力(li)(li)減(jian)(jian)弱、尿量(liang)(liang)(liang)(liang)(liang)(liang)減(jian)(jian)少(shao)而血(xue)(xue)(xue)容量(liang)(liang)(liang)(liang)(liang)(liang)已為(wei)補(bu)足的(de)(de)休(xiu)克患者(zhe)尤為(wei)適用(yong)。
【貯藏】
遮光，密閉保存。
【規格】
2ml:20mg
【有效期】
24個月
【批準文號】
國藥準(zhun)字H32023366
【說明書修訂日期】
2011年05月18日(ri)
【生產企業】
企業名稱：亞邦醫藥股份有限公司
企業(ye)簡(jian)稱(cheng)：南中(zhong)醫大藥業(ye)
【適應癥】用于：①關節炎(yan)，可緩(huan)解(jie)疼痛和腫脹；②軟組織損傷和炎(yan)癥；③解(jie)熱；④其他(ta)：用于治療偏(pian)頭痛、痛經(jing)、手(shou)術后痛、創傷后痛等。
